Cell cycle: Driving the centrosome cycle
نویسنده
چکیده
Cyclin-dependent kinases (Cdks) control major transitions as cells pass through the cell cycle. It has recently been shown that centrosome duplication in vertebrates requires Cdk2 activity and can be driven solely by Cdk2-cyclin E complexes.
منابع مشابه
Regulated HsSAS-6 levels ensure formation of a single procentriole per centriole during the centrosome duplication cycle.
Centrosome duplication involves the formation of a single procentriole next to each centriole, once per cell cycle. The mechanisms governing procentriole formation and those restricting its occurrence to one event per centriole are poorly understood. Here, we show that HsSAS-6 is necessary for procentriole formation and that it localizes asymmetrically next to the centriole at the onset of proc...
متن کاملThe FA2 gene of Chlamydomonas encodes a NIMA family kinase with roles in cell cycle progression and microtubule severing during deflagellation.
The NIMA kinases are one of several families of kinases that participate in driving the eukaryotic cell cycle. NIMA-related kinases have been implicated in G2/M progression, chromatin condensation and regulation of the centrosome cycle. Here we report the identification of a new member of this family, FA2, from Chlamydomonas reinhardtii. FA2 was originally discovered in a genetic screen for def...
متن کاملInvestigating the Impact of Driving Cycle on 3-way Catalyst Degradation and Emission Characteristics of ICEV
Internal Combustion Engine Vehicles or ICEVs play a major role in air pollution for big cities like Tehran. Catalyst converters manage to contain much of the generated pollution from combustion and are considered as a mandatory part of any vehicle. Manufacturer guidelines clarify a certain mileage for catalyst to be regarded as completely degraded and thus unable to contain harmful gasses from ...
متن کاملVerification of IVE Model for SAIPA Co. Fleet Emission
To determine the amount of air pollutants, produced by Iranian automakers, and compare it with old and retrofitted vehicles have become one of the important tools of urban management. The present research uses International Vehicle Emission (IVE) modeling software in order to verify SAIPA Co. fleet emissions, based on Euro 4 emission standard (SAIPA Co. recognized as a superior Iranian brand in...
متن کاملModelling and Optimization of Toroidal Continuously Variable Transmission in ECE Driving Cycle
In the present study, the aim is to optimize full and half toroidal continuously variable transmission (CVT) in order to minimize the vehicle fuel consumption (FC) in ECE driving cycle. First, the model of both CVTs’ efficiency is presented. The control strategy of CVTs speed ratio based on minimizing the vehicle FC is introduced, and the algorithm of calculating the vehicle FC is shown. Afterw...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Current Biology
دوره 9 شماره
صفحات -
تاریخ انتشار 1999